Sébastien Bolze has broad experience in drug development from discovery screening to first-in-man clinical trials. Dr. Bolze was global head of the preclinical candidate selection unit at Solvay Pharmaceuticals, a multidisciplinary unit providing support to research projects from optimization of validated hits to delivery of candidates for preclinical development. From 2003 to 2006, he was executive head of the ADME department at Fournier Pharma. He acquired strong organizational and managerial experience in research projects within a multidisciplinary and global environment. Dr. Bolze has also co-authored numerous research publications and posters.

Dr. Bolze is a Pharmacist and holds a PhD in Pharmacokinetics and Drug Metabolism from the University of Lyon I (France).

Sophie Bozec joined Merck KGaA in 1998 where she managed a drug discovery team in a pharmacology department. Dr. Bozec has acquired a strong experience for managing research projects from target identification to preclinical development candidates. She has developed her knowledge in models (in vivo and in vitro) used in research programs for identifying preclinical development candidates in the diabetes field. She acquired a solid expertise in metabolic diseases particularly in the diabetes field. This experience in pharmacology led Dr. Bozec to support a clinical development compound for all preclinical pharmacology aspects.

Dr. Bozec holds a PhD in Nutrition, Metabolism and Obesity from the Paris VII University.

Pascale Fouqueray joined Merck KGaA in 2000 from Paris VII University, where she was Assistant Professor of physiology. At Merck KGaA, Dr. Fouqueray's activities were centered on metabolism, with a particular focus on diabetes and obesity but also including lipids and uric acid metabolism. Dr. Fouqueray was responsible for the clinical development of compounds for the treatment of diabetes and gout disease, working on strategies to define and reach proof-of- concept and investigate mechanisms of action.

Dr. Fouqueray graduated from medical school at the University of Angers (France) and then specialized in Endocrinology and Metabolism at the University of Paris V. She holds a PhD from the University of Paris XI.